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Number needed to treat calculator

Enter events and totals for the treatment and control groups.

Absolute NNT or NNH: —

Fill in the fields above — the result is computed on this page.

Direction: 1 = NNT, −1 = NNH
—
Experimental event rate EER
—
Control event rate CER
—
Risk difference CER − EER
—
Relative risk RR
—
Relative risk reduction RRR
—
Odds ratio OR
—

Event table

Group Event No event Total Risk
Fill in the fields above — the result is computed on this page.
What do these numbers mean?
  • For practical interpretation, NNT or NNH is commonly rounded cautiously to a whole person.
  • Always report the follow-up period and event definition.

The calculator gives point estimates without confidence intervals and does not adjust for group differences. Equal risks imply an infinite NNT and are returned as no finite result. This tool does not replace clinical judgment.

How do I use this page?
  1. Enter event counts and totals for both groups.
  2. Inspect the risk-difference sign.
  3. Read NNT for benefit or NNH for harm.

What this page does not do: The calculator gives point estimates without confidence intervals and does not adjust for group differences. Equal risks imply an infinite NNT and are returned as no finite result. This tool does not replace clinical judgment.

Further reading

Theory — what are NNT and NNH?

NNT, the number needed to treat, is the inverse of the absolute risk reduction. It tells you how many people must receive the intervention to prevent one additional event over a given period. When risk in the intervention group is higher than in the control group, the same calculation describes NNH, the number needed to harm. The figure should be reported alongside a confidence interval rather than as a single rounded number.

Frequently asked questions

Should NNT be rounded?
For practical decisions it is commonly rounded up for benefit; also report the unrounded estimate and confidence interval.
Why does follow-up time matter?
Risk and NNT depend on the period during which events were counted.

See also

← All calculators

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